She took to to tell fans she was undergoing treatment, having previously opened about struggling with substance abuse and anxiety last year.
There were 309 reports of irritability, 256 reports of personality change and 68 of paranoia.
But such medicines can harbour a more insidious danger: they may make you aggressive, violently jealous, suicidal or even homicidal.
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Pfizer Canada says it stands by Champix.
The report warns that hormonal contraceptives may, ironically, ruin relationships.
Likewise, he says, pharmaceutical companies must be much more open with the results of their own clinical trials.